Year: 2024
Type: other
Abstract: This chapter discusses the normal physiology of musculoskeletal system in the neonatal period. In accordance with Wolff's law, bone is an intensely dynamic tissue that models and remodels throughout life dependent on the loads placed on it. In short, low strain leads to osteocyte apoptosis and bone resorption whereas high strain results in deposition of bone and an increase in bone mass. The articular cartilage is also part of articularepiphyseal complex, which is the growth cartilage responsible for the formation of the secondary ossification center in the postnatal period. The physis is also a vascularized growth cartilage that undergoes endochondral ossification with calcification of cartilage, invasion by blood vessels. Vessels in cartilage have a monopodial branching pattern, and vessels in epiphyseal and metaphyseal bone have a monopodial and dichotomous branching pattern.
Author: Ashlee Watts
Language: English
Topic: Bone Metabolism and Diseases
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4391694853