Year: 2024
Type: article
Study design: Observational Study
Abstract: We aimed to evaluate differences in dietary factors between young-onset (diagnosed at ages <50) and older-onset colorectal cancer (CRC). CRC patients diagnosed from 1998 to 2018 reported to the Puget Sound Surveillance, Epidemiology, and End Results registry were recruited using mail and telephone. Consented patients completed questionnaires assessing demographics, medical history, and CRC risk factors, including dietary factors. We used multi-variable logistic regression to calculate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) comparing dietary intake in young-onset vs. older-onset CRC. Analyses included 1,087 young- and 2,554 older-onset CRC patients. Compared to older-onset CRC, young-onset CRC patients had lower intake of vegetables (OR for highest intake vs. lowest = 0.59 CI: 0.55, 0.64) and fruit (OR for highest intake vs. lowest = 0.94 CI: 0.88, 0.99) and higher intake of processed meat (OR for highest intake vs. lowest = 1.82 CI: 1.11, 2.99) and spicy food (OR for highest intake vs. lowest = 1.69 CI: 1.09, 2.61). There was no statistically significant difference between young- and older-onset CRC patients for red meat consumption. Dietary patterns differed between young- and older-onset CRC; young-onset CRC patients had lower intake of vegetables and fruit and higher intakes of processed meat and spicy food.
Source: Nutrition and Cancer
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1684996355, G2087751801, SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAM, SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS (SEER) PROGRAM., Training and Research in Colon Cancer Survival, Seattle Colorectal Cancer Family Registry (CFR), G391480630, G5442954921, Methods for Analyzing Cancer Somatic Mutation Data, G5788305929, G6642003361, G6668393052, G6918134795, G804866679, G8550955980, G8717088952, G9000064876, G9000111169, Contributing Factors and Consequences of Cancer Health Disparities, G934068040
OpenAlex ID: W4391783153