Work

HHC-induced psychosis: a case series of psychotic illness triggered by a widely available semisynthetic cannabinoid

Year: 2024

Type: article

Abstract: Use of both cannabis and synthetic cannabinoids has been regularly linked to the development of psychotic illness. Thus, semisynthetic cannabinoids such as hexahydrocannabinol (HHC), which have a similar neurobiological profile to delta-9-THC, may also be expected to lead to psychotic illness. However, no such relationship has yet been reported in scientific literature. HHC is readily available online and in many vape shops in Ireland. Here, we present two cases of psychotic illness which appear to have been precipitated by use of legally purchased HHC and discuss its psychotogenic role and factors linked to its current widespread availability.

Source: Irish Journal of Psychological Medicine

DOI: 10.1017/ipm.2024.3

Authors: Brian O’Mahony, Andrew O’Malley, Olan Kerrigan, Colm McDonald

Institutions: University Hospital Galway, Mercy University Hospital, Ollscoil na Gaillimhe – University of Galway

Language: English

Topic: Cannabis and Cannabinoid Research

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,450