Work

Screening oral drugs for their interactions with the intestinal transportome via porcine tissue explants and machine learning

Year: 2024

Type: article

Source: Nature Biomedical Engineering

DOI: 10.1038/s41551-023-01128-9

Authors: Yunhua Shi, Daniel Reker, James D. Byrne, Ameya R. Kirtane, Kaitlyn Hess, Zhuyi Wang, Natsuda Navamajiti, Cameron C. Young, Zachary Fralish, Zilu Zhang, Aaron Lopes, Vance Soares, Jacob Wainer, Thomas von Erlach, Lei Miao, Robert Langer, Giovanni Traverso

Institutions: Brigham and Women's Hospital, Harvard University, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology, Duke University, University of Iowa, Chulalongkorn University

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering

Awards: A new high-throughput gastrointestinal tract explant platform for drug formulation discovery and metabolic disease modulation, G4388536804, G9000163483

OpenAlex ID: W4391960362

FWCI: 1.371

Cites: 67

Cited by: 9

Related to: 10