Work

Evaluation of visual function and quality of life in patients with age-related macular degeneration after treatment

Year: 2018

Type: article

Abstract: AIM: To evaluate the anatomic parameters, visual function and quality of life(QOL)in patients with age-related macular degeneration(ARMD)who were transferred from Ranibizumab to Conbercept. METHODS: Twenty patients(29 eyes)with angiogenic ARMD who were treated in our hospital in January 2016 to August 2017 because of the poor therapeutic effect of ranibizumab were selected. The main outcome measures were BCVA, contrast sensitivity(CS), mean changes of central retinal thickness(CRT)and 25 visual function questionnaires(NEI VFQ-25)from baseline to 4mo. The statistical data were analyzed by paired t test to compare the mean values of continuous variables. RESULTS: At 4mo after treatment, BCVA were significantly improved compared to before treatment(P<0.05). The CRT detected by OCT decreased(P<0.05). CS at different frequency was better than before treatment(P<0.05). NEI VFQ-25 scores were higher than before treatment(P<0.05). CONCLUSION: In the treatment of age-related macular degeneration with conbercept, the visual function and the quality of life are remarkably improved.

Source: DOAJ (DOAJ: Directory of Open Access Journals)

DOI: 10.3980/j.issn.1672-5123.2018.8.41

Authors: Peng Li, Qian-Yan Kang, Li Wang, Dan-Yu Gao

Institutions: People 's Liberation Army 451 Hospital, First Affiliated Hospital of Xi'an Jiaotong University, Chinese People's Liberation Army, Xi'an Jiaotong University, Xi'an Medical University

Language: English

Topic: Retinal Diseases and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4392136465