Work

Author Response: DNA methylation-environment interactions in the human genome

Year: 2024

Type: peer-review

Abstract: A massively parallel reporter assay, mSTARR-seq, reveals widespread DNA methylation-environment interactions across the genome, prioritizing CpG sites identified in epigenome-wide association studies that may be most relevant to biological embedding.

Source: eLife

DOI: 10.7554/elife.89371.3.sa3

Authors: Rachel A Johnston, Katherine A Aracena, Luis B Barreiro, Amanda J Lea, Jenny Tung

Institutions: Broad Institute, Duke University, Zoo New England, University of Chicago, Princeton University, Max Planck Institute for Evolutionary Anthropology

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,500

Funders: Alfred P. Sloan Foundation, North Carolina Biotechnology Center, National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1151036099, G280038635, Early adversity and DNA methylation in a primate model of stress and development., G5306657525, G548326652, Quantifying the genome-wide functional consequences of DNA methylation associated with early life adversity.

OpenAlex ID: W4392157359

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