CDKN1B(p27kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors
Work
Year: 2024
Type: preprint
Abstract: ABSTRACT The mitotic inhibitor docetaxel (DTX) is often used to treat endocrine-refractory metastatic breast cancer, but initial responses are mitigated as patients eventually have disease progression... more
Authors E. Philip Horwitz, Taronish D. Dubash, Annamária Szabolcs, Ben S. Wittner, Johannes Kreuzer +14 more
Institutions Center for Cancer Research, Harvard University, Massachusetts General Hospital, Broad Institute, Howard Hughes Medical Institute
Cites: 74
Cited by:
Related to: 10
Citation percentile (by year/subfield):
Subfield: Cell Biology
Domain: Life Sciences
Sustainable Development Goal Good health and well-being
Open Access status: green