Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia
Year: 2024
Type: article
Abstract: International audience
Source: Haematologica
Authors: Shannon L. Carey-Smith, Maryam H. Simad, Kunjal Panchal, Carlos Aya-Bonilla, Hannah Smolders, Sang Lin, Jesse D. Armitage, Vivien T. Nguyen, Kathryn Bentley, Jette Ford, Sajla Singh, Joyce Oommen, Anouchka P. Laurent, Thomas Mercher, John D. Crispino, Andrew P. Montgomery, Michael Kassiou, Thierry Besson, Emmanuel Deau, Laurent Meijer, Laurence C. Cheung, Rishi S. Kotecha, Sébastien Malinge
Institutions: The Kids Research Institute Australia, Curtin University, Inserm, Institut Gustave Roussy, St. Jude Children's Research Hospital, The University of Sydney, Centre National de la Recherche Scientifique, Laboratoire COBRA, Université de Rouen Normandie, Institut National des Sciences Appliquées Rouen Normandie, The University of Western Australia, Princess Margaret Hospital for Children, Perth Children's Hospital
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,157
Funders: Indian National Science Academy, Australian Government, Bpifrance, European Commission, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Curtin University of Technology, Centre National de la Recherche Scientifique, Université de Rouen, Institut Gustave-Roussy, Institut Carnot Santé Animale, Région Normandie, Medical Research Council, National Health and Medical Research Council, Cancer Council Western Australia, European Regional Development Fund, Curtin Health Innovation Research Institute, Curtin University, HORIZON EUROPE European Innovation Council
Awards: LCTB-21: A DYRK1A protein kinase inhibitor for treatment of cognitive decline in Down Syndrome., G1406946691, G1576599217, XLChem, Synthesizing our future, G2900821844, G434337789, Gene overdosage and comorbidities during the early lifetime in Down Syndrome, G4656594441, Small molecule therapeutics for brain disorders, G5976147578, G7141076302, Synthèse Organique : des molécules au vivant
OpenAlex ID: W4392287374