Work

ATEMPTing to navigate between “lower is better” and “less is more”

Year: 2024

Type: article

Abstract: Hypertension is a leading risk factor for dementia, cardiovascular disease, and death in older adults. Although intensive blood pressure control effectively reduces cardiovascular morbidity and mortality, older and frail adults might be more susceptible to adverse effects such as hypotension, falls, and electrolyte abnormalities. Most of the landmark hypertension trials that inform current clinical guidelines have excluded older adults or those with significant multimorbidity, polypharmacy, disability, or other factors that can limit life expectancy or the ability to strictly adhere to burdensome study protocols.

Source: The Lancet Healthy Longevity

DOI: 10.1016/s2666-7568(24)00024-2

Authors: Nicholas M Pajewski, Jordana B Cohen

Institutions: Atrium Health Wake Forest Baptist, Wake Forest University Health Sciences, Wake Forest University, University of Pennsylvania

Language: English

Topic: Blood Pressure and Hypertension Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,780