Hypokalemia Induced Partial Nephrogenic Diabetes Insipidus: A Case Report
Year: 2024
Type: article
Study design: Case Report
Abstract: ABSTRACT: Diabetes insipidus is a condition characterised by a large volume of diluted urine production and increased thirst. In this case report, a 49-year-old gentleman presented with 3 months of polyuria and polydipsia. He had a repeated history of hypokalemia. On the evaluation of polyuria and polydipsia, he was diagnosed with partial nephrogenic diabetes insipidus based on his inability to concentrate urine after a water deprivation test and his less than 50% response to exogenous desmopressin. On the evaluation of recurrent hypokalemia, the investigation reports met biochemical criteria for the diagnosis of Gitelman syndrome. He was encouraged to increase his fluid intake as required, and potassium chloride supplementation relieved his symptoms. This case report demonstrates the reversibility of nephrogenic diabetes insipidus with a correction of hypokalemia.
DOI: 10.31729/jnma.8501
Authors: Anil Nepali, Prakriti Adhikari, Amit Shah, Shailes Paudel, Prakriti Bhandari
Institutions: Patan Academy of Health Sciences, Kathmandu University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4392365817