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Figure S7 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses In Vivo

Year: 2024

Type: other

Abstract: Spider plots of tumor growth. Nude mice bearing LS174T xenografts were injected with 4 doses of 10 mg/kg (marked with arrows on day 0, 4, 8, and 12) of either LG, XAb-SN-38, or vehicle. Individual growth curves for all mice are shown.

DOI: 10.1158/1535-7163.25338052.v1

Authors: Ian Nessler, Baron Rubahamya, Anna Kopp, Scott Hofsess, Thomas M. Cardillo, Nalini Sathyanarayan, Jennifer Donnell, Serengulam V. Govindan, Greg M. Thurber

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4392383601

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