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FIGURE 5 from Identification and Characterization of a Small Molecule Bcl-2 Functional Converter

Year: 2024

Type: other

Abstract: BFC1108 induces cell death across multiple Bcl-2–expressing TNBC cell lines to a greater extent than ABT199. Cell death percentage is calculated based upon viability assay after 72 hours treatment at the indicated BFC1108 concentrations.

DOI: 10.1158/2767-9764.25338572

Authors: Prasad R. Kopparapu, Martin C. Pearce, Christiane V. Löhr, Cathy Duong, Hyo Sang Jang, Shanthakumar Tyavanagimatt, Edmond F. O'Donnell, Harikrishna Nakshatri, Siva K. Kolluri

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4392384385

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