Work

On‐Chip Reconstitution of Uniformly Shear‐Sensing 3D Matrix‐Embedded Multicellular Blood Microvessel (Adv. Funct. Mater. 10/2024)

Year: 2024

Type: article

Abstract: Organs-on-Chips In article number 2304630, Kambez H. Benam and co-workers present the design, optimization, and validation of a robust and highly reproducible methodology for constructing centimeters-long cross-sectionally rounded, extracellular matrix (ECM)-embedded, multicellular microvasculature (MV) in an Organ-on-a-Chip device – a platform named “ECM MV-Chip”. This living system allows culture of primary human-derived, organ-specific vascular endothelial cells and stromal cells, and fine control of ECM mechanical properties and composition.

Source: Advanced Functional Materials

DOI: 10.1002/adfm.202470054

Authors: Quoc Vo, Kaely A. Carlson, Peter M. Chiknas, Chad N. Brocker, Luis DaSilva, Erica Clark, Sang Ki Park, A. Seun Ajiboye, Eric M. Wier, Kambez H. Benam

Institutions: University of Pittsburgh, United States Food and Drug Administration, Center for Tobacco Products

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4392473271

FWCI: 0.21

Cites:

Cited by: 2

Related to: 10