P186: The earliest sign of hypogonadotropic hypogonadism: The importance of genetic screening and evaluation in individuals with microphallus
Year: 2024
Type: article
Abstract: Microphallus is a congenital difference in male presenting individuals defined as a stretched penile length of less than 2.5 standard deviations (SDs) below the mean for age. As an anomaly affecting the genital system, this is a finding that meets criteria for a variation of sex characteristic/difference of sex development (VSC/DSD). Currently, 37 OMIM genes have microphallus as associations, most of which are related to Hypogonadotropic Hypogonadism (HH). HH can be defined as failure of the normal episodic GnRH secretion.
Source: Genetics in Medicine Open
Authors: Jacqueline Leonard, Marissa Kilberg, Maria Vogiatzi, Chris Gibson, Jason Van Batavia, Leela Morrow, Vaneeta Bamba, Sara Pinney, Christopher Gray, Cara Skraban, Kosuke Izumi, Louise Pyle
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,200
OpenAlex ID: W4392606773