Data from Cisplatin Depletes TREX2 and Causes Robertsonian Translocations as Seen in TREX2 Knockout Cells
Work
Year: 2023
Type: preprint
Abstract: <div>Abstract<p>Cisplatin, an anticancer drug, forms DNA interstrand cross-links (ICL) that interfere with replication, whereas TREX2 is a 3′→5′ exonuclease that removes 3′ mismatched nucl... more
Authors Ming-Jiu Chen, Lavinia C. Dumitrache, Danny Wangsa, Sheng‐mei Ma, Hesed Padilla‐Nash +2 more
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Related to: 10
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Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Sustainable Development Goal Good health and well-being
Open Access status: green