Year: 2024
Type: review
Abstract: Exosomes, which are small vesicles enclosed by a lipid bilayer and released by many cell types, are widely dispersed and have garnered increased attention in the field of regenerative medicine due to their ability to serve as indicators of diseases and agents with therapeutic potential. Exosomes play a crucial role in mediating intercellular communication through the transfer of many biomolecules, including proteins, lipids, RNA, and other molecular constituents, between cells. The targeted transport of proteins and nucleic acids to specific cells has the potential to enhance or impair specific biological functions. Exosomes have many applications, and they can be used alone or in combination with other therapeutic approaches. The examination of the unique attributes and many functions of these factors has emerged as a prominent field of study in the realm of biomedical research. This manuscript summarizes the origins and properties of exosomes, including their structural, biological, physical, and chemical aspects. This paper offers a complete examination of recent progress in tissue repair and regenerative medicine, emphasizing the possible implications of these methods in forthcoming tissue regeneration attempts.
Source: Theranostics
DOI: 10.7150/thno.93088
Authors: Weikang Hu, Wang Wang, Zesheng Chen, Yun Chen, Zijian Wang
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,671
Funders: Health Commission of Hubei Province, National Natural Science Foundation of China, Natural Science Foundation of Hubei Province, Wuhan University, Zhongnan Hospital of Wuhan University, National Postdoctoral Program for Innovative Talents, Fundamental Research Funds for the Central Universities
OpenAlex ID: W4392830963