Work

Coumarin–furo[2,3- d ]pyrimidone hybrid molecules targeting human liver cancer cells: synthesis, anticancer effect, EGFR inhibition and molecular docking studies

Year: 2024

Type: article

Abstract: Coupling a furopyrimidone scaffold with coumarin through a hydrazide linker can effectively improve their synergistic anticancer activity targeting HepG2.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d3md00668a

Authors: Tianshuai Wang, Yumeng Gao, Fengxu Wu, Lun Luo, Junkai Ma, Yanggen Hu

Institution: Hubei University of Medicine

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Hubei Provincial Department of Education

Award: G7258141069

OpenAlex ID: W4392961343

FWCI: 1.101

Cites: 49

Cited by: 8

Related to: 10