Training the Next Generation of Data Monitoring Committee Members
Year: 2024
Type: review
Abstract: Clinical trials are vital for assessing therapeutic interventions. The associated data monitoring committees (DMCs) safeguard patient interests and enhance trial integrity, thus promoting timely, reliable evaluations of those interventions. We face an urgent need to recruit and train new DMC members. The HFC (Heart Failure Collaboratory), a multidisciplinary public-private consortium of academics, trialists, patients, industry representatives, and government agencies, is working to improve the clinical trial ecosystem. The HFC aims to improve clinical trial efficiency and quality by standardizing concepts, and to help meet the demand for experienced individuals on DMCs by creating a standardized approach to training new members. This paper discusses the HFC's training workshop, and an apprenticeship model for new DMC members. It describes opportunities and challenges DMCs face, along with common myths and best practices learned through previous experiences, with an emphasis on data confidentiality and need for quality independent statistical reporting groups.
Source: JACC Heart Failure
Institutions: University of Washington, Duke University, Duke Medical Center, University of Colorado Anschutz, Duke Clinical Research Institute, University of Central Florida, Vanderbilt University, Brigham and Women's Hospital, The Ohio State University Wexner Medical Center, The Ohio State University, University of Wisconsin–Madison, Vanderbilt University Medical Center
Language: English
Topic: Ethics in Clinical Research
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,750
OpenAlex ID: W4393166176