Year: 2024
Type: conference-abstract
Abstract: High density lipoproteins (HDL) are protein-lipid complexes that aid in cholesterol efflux, a process in which HDL particles interact with ATP-binding cassette transporters ABCA1 and ABCG1 to remove excess cholesterol from macrophages and peripheral tissues for eventual disposal. The major protein on HDL, apolipoprotein AI (apoAI), exists in lipid-free and lipid-bound states. When bound to phospholipids in nascent discoidal HDL, it contains 10 ⍺-helices (H1-H10) that wrap around the hydrophobic lipid tails.
Source: Journal of Biological Chemistry
Authors: Kasandra Khiev, Kyle Meyer, Vasanthy Narayanaswami
Institution: California State University, Long Beach
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,800
OpenAlex ID: W4393178707