Toward a Practical Catalyst for Direct Amidation of Carboxylic Acids with Pyridine‐Borane Complexes
Year: 2024
Type: article
Abstract: Pyridine‐borane complex was widely used as a reducing agent, but the exploration of such reagent as a catalyst for amidation of carboxylic acids are still unknown. Here we reported the first example of direct amidation of carboxylic acids catalyzed by pyridine‐borane complexes. This protocol features a low catalyst loading (0.2–10 mol %), broad substrate scope, good functional group compatibility, and affording the amides in high yields.
Source: ChemistrySelect
Institution: Hubei University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4393233519