BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
Work
Year: 2024
Type: article
Abstract: Reprogramming to pluripotency is associated with DNA damage and requires the functions of the BRCA1 tumor suppressor. Here, we leverage separation-of-function mutations in BRCA1/2 as well as the physi... more
Source: Cell Reports
Authors Daniela Georgieva, Ning Wang, Angelo Taglialatela, Stepan Jerabek, Colleen R. Reczek +8 more
Institutions Columbia University Irving Medical Center, New York Stem Cell Foundation, Columbia University, Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Cancer Genetics (United States) +1 more
Cites: 73
Cited by: 4
Related to: 10
FWCI: 3.233
Citation percentile (by year/subfield): 100
Subfield: Molecular Biology
Domain: Life Sciences
Sustainable Development Goal Life on land
Open Access status: gold
APC paid (est): $5,200