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Supplementary Figure S9 from Development of a [89Zr]Zr-labeled Human Antibody using a Novel Phage-displayed Human scFv Library

Year: 2024

Type: supplementary-materials

Abstract: Supplementary Figure 9. A. HPLC-SEC analysis of L111 and L111-DFO on an Agilent 1200 series HPLC system using a Zorbax GF-250 9.4 mm ID x 25 cm column (Agilent). DFO conjugation did not change the retention time of the antibody, and no aggregation was observed. B. iTLC showing the radiochemical purity of the radiolabeled L111 antibody. C. Radio-HPLC confirming the radiolabeling of the L111 antibody with [89Zr]Zr.

DOI: 10.1158/1078-0432.25515655

Authors: Abhay K. Singh, Calvin D. Lewis, Cristian A.W.V. Boas, Philipp Diebolder, Prashant N. Jethva, Aaron Rhee, Jong Hee Song, Young Ah Goo, Shunqian Li, Michael L. Nickels, Yongjian Liu, Buck E. Rogers, Vaishali Kapoor, Dennis E. Hallahan

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

OpenAlex ID: W4393391338

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