Work

Olfactory bulb snRNAseq dataset for Team Schlossmacher- ASAP

Year: 2023

Type: dataset

Abstract: C57BL/6 mice were nasally inoculated with either a control AAV (AAV-EF1a-TdTomato, B1-4) or an experimental AAV expressing humanized mutant alpha-synuclein (AAV-EF1a-SNCA(A53T), A1-4). The mice were 8 weeks of age at the time of inoculation and the virus was expressed for 4 weeks before the mice were sacrificed and the olfactory bulbs were collected for snRNAseq. Viral transduction of olfactory sensory neurons was confirmed in all 8 samples via cryosectioning of the contralateral olfactory bulb.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.8219740

Authors: Belfort, Benjamin, Garza, Alexandra, Chen, Hu, Zhandong Liu, Arenkiel, Benjamin

Institution: Baylor College of Medicine

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4393428487

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