Work

Pathways enriched in downstream target genes of miRNAs associated with NT-proBNP and OPN

Year: 2019

Type: dataset

Abstract: The full set of 30 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways that were significantly enriched (FDR-adjusted p<0.01) in the predicted mRNA targets of either the OPN- or NT-proBNP-associated miRNAs; 21 of these pathways were significantly enriched in both sets of targets. KEGG: Kyoto Encyclopedia of Genes and Genomes; miRNAs: microRNAs; NT-proBNP: N-terminal pro B-type natriuretic peptide; OPN: osteopontin

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.2630503

Authors: Kwee, Lydia Coulter, Grass, Elizabeth, Gregory, Simon G., Lenden M. Bowsman, Haas, Joseph V., Duffin, Kevin L., Chan, Mark Y., Svati H. Shah, Roe, Matthew T., E. Magnus Ohman, Fox, Keith A.A., White, Harvey D., Armstrong, Paul W.

Institutions: Duke University, Duke Medical Center, Eli Lilly (United States), National University of Singapore, Duke Clinical Research Institute, University of Edinburgh, Auckland City Hospital, University of Alberta, Canadian VIGOUR Centre

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4393668000

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