Work

FIGURE 7 from Versican Associates with Tumor Immune Phenotype and Limits T-cell Trafficking via Chondroitin Sulfate

Year: 2024

Type: other

Abstract: Effect of CS toward T-cell invasion. A, CS MS completed on the crude and enriched protein from HMF3S and HCC38 cell lines. CS isomers and A/C ratio determined. B, Transwell assay completed with 5 µg of each protein sample. Each sample was treated with ChABC for comparison. Heat map shows level of T cells invaded over time for one T-cell donor. Graphs show the level of migrated cells for HMF3S (C) and HCC38 (D) with error bars showing replicates with different T-cell donors.

DOI: 10.1158/2767-9764.25534442

Authors: Priyanka Hirani, Jacqueline McDermott, Vinothini Rajeeve, Pedro R. Cutillas, J. Louise Jones, Daniel J. Pennington, Thomas N. Wight, Salvatore Santamaria, Kimberly M. Alonge, Oliver M.T. Pearce

Language: English

Topic: Proteoglycans and glycosaminoglycans research

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4393899102

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