Additional file 2: of Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner
Year: 2019
Type: dataset
Abstract: Associations of candidate gene expression in fetal placenta with maternal U-As. Multivariable linear regression analysis was performed to determine the association between log-transformed maternal U-As and log-transformed fetal placental expression of epigenetic candidate genes, in A) the unstratified cohort, B) males, and C) females. Analyses were adjusted for maternal age at enrollment. P values before and after FDR adjustment are shown (columns C-D). The effect of adjustment for urinary creatinine was also determined, by comparing the standardized beta values obtained from the subset of participants for which urinary creatinine data were available (â standardized_subset_betaâ , column P) with the equivalent values after adjustment for urinary creatinine (â standardized_subset_betaâ , column Q). Results of goodness-of-fit tests are also shown (columns S-T). (XLSX 124 kb)
Source: Figshare
Authors: Winterbottom, Emily, Moroishi, Yuka, Halchenko, Yuliya, Armstrong, David, Beach, Paul, Nguyen, Quang, Capobianco, Anthony, Ayad, Nagi, Marsit, Carmen, Li, Zhigang, Karagas, Margaret, Robbins, David
Language: English
Subfield: Environmental Chemistry
Field: Environmental Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4394088454