Work

Additional file 12 of C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation

Year: 2021

Type: dataset

Abstract: Additional file 12: Table S4. (A) Dysregulated pathways driven by RELAFUS1target genes in TSS±10kb in 293T-RELAFUS1 cells. (B) Dysregulated pathways driven by RELAFUS1 target genes in TSS ±10kb in H1203-mEPN cells. (C) Dysregulated pathways driven by RELAFUS1-S486E target genes in TSS ±10kb in 293T-RELAFUS1-S486E cells. (D) Up-regulated genes in ST-EPN-RELA relative to ST-EPN-YAP1 subgroup (DEGs: RELAup vs YAP1, logFC>1, FDR < 0.05) (E) Down-regulated genes in ST-EPN-RELA relative to ST-EPN-YAP1 subgroup (DEGs: RELA vs YAP1up, logFC < -1, FDR < 0.05) (F) Up-regulated pathways in ST-EPN-RELA subgroup (G) Up-regulated pathways in ST-EPN-YAP1 subgroup. (XLSX 546 KB)

Source: Figshare

DOI: 10.6084/m9.figshare.14183618

Authors: Ozawa, Tatsuya, Kaneko, Syuzo, Szulzewsky, Frank, Zhiwei Qiao, Takadera, Mutsumi, Narita, Yoshitaka, Kondo, Tadashi, Holland, Eric C., Hamamoto, Ryuji, Ichimura, Koichi

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4394201960

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