Work

Supplementary Materials for: The Chagas Antigen and Epitope Atlas

Year: 2022

Type: supplementary-materials

Abstract: The Chagas Antigen and Epitope Atlas contains experimentally-derived information on the antigenicity of Trypanosoma cruzi peptides. Antigenicity was measured on peptide arrays assayed with serum samples from Chagas disease subjects and matched negative controls. High-density peptide arrays with custom designs were to display peptides derived from two complete T. cruzi proteomes. Sampling of subjects from diverse human populations complements the antigenicity information of proteins and peptides with seroprevalence information across the Americas.

Source: Figshare

DOI: 10.6084/m9.figshare.19991021

Authors: Agüero, Fernán, Ricci, Alejandro, Bracco, Leonel

Language: English

Topic: Trypanosoma species research and implications

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Award: HIGH-THROUGHPUT EPITOPE DISCOVERY: USE OF NEXT-GENERATION PEPTIDE CHIPS FOR FAST IDENTIFICATION AND FINE MAPPING OF DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CHAGAS DISEASE

OpenAlex ID: W4394222818

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