Supporting data for "On the origin and evolution of RNA editing in metazoans"
Year: 2023
Type: dataset
Abstract: Extensive adenosine-to-inosine (A-to-I) editing of nuclear-transcribed RNAs is the hallmark of metazoan transcriptional regulation, and is fundamental to numerous biochemical processes. Here we explore the origin and evolution of this regulatory innovation, by quantifying its prevalence in 22 species that represent all major transitions in metazoan evolution. Files provided in this dataset: 1. Genebody_Anno.tar.gz : Refined gene annotations of the 22 species used in this study in gene transfer format (GTF). 2. Repeat_Anno.tar.gz : Refined repeat annotation of the 22 species used in this study in gene transfer format (GTF). 3. Go_Anno.tar.gz : Gene ontology annotations of coding genes of the 22 species used in this study. 4. BlastBesthit.tar.gz : Best hit of coding genes of the 22 species used in this study returned by Blast searching to the NCBI NR database. 5. ResTable.tar.gz : RNA editing sites set of the 22 species identified in this study. 6. HyperEditingManual.tar.gz : Important manual scripts and pipelines including hyper-editing sites identification used in this study.
Source: Figshare
Institutions: Tongji University, Central South University, Northeast Normal University, Chinese Academy of Medical Sciences & Peking Union Medical College, Fudan University, Jilin Agricultural University, Xiangya Hospital Central South University, Harvard University, Jilin University, Tianjin Medical University Cancer Institute and Hospital, Sun Yat-sen Memorial Hospital, Jiangsu Province Hospital, Nanjing Medical University, University of Chinese Academy of Sciences, Institució Catalana de Recerca i Estudis Avançats, Universitat de Barcelona, BGI Group (China), University of Copenhagen, Kunming Institute of Zoology, Chinese Academy of Sciences
Language: English
Topic: RNA regulation and disease
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4394310199