Additional file 1 of Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity
Year: 2022
Type: dataset
Abstract: Additional file 1: Supplemental Table 1. Differentially expressed proteins in the soluble AD brain proteome. TBS-soluble extracts were prepared from brain tissue described in Table 1, and mass spectrometry used to quantify proteins. Differential expression of individual proteins was analyzed between AD vs. LP-NCI (A) and AD vs. HP-NCI (B). Many more proteins were differentially expressed in the LP-NCI vs. AD comparison than in the HP-NCI vs. AD comparison. Unpaired t-test with Welch correction, two-stage step-up, FDR < 0.05.
Source: Figshare
Institutions: Harvard University, Yunnan Normal University, Zhejiang Sci-Tech University, Anhui University, Army Medical University, Harbin Medical University, Jinan University, Gansu Agricultural University, Guangdong Medical College, Xuzhou Medical College, Jilin University, Chinese Academy of Medical Sciences & Peking Union Medical College, Washington University in St. Louis, Sichuan University, Southern University of Science and Technology, University of Florida, Soochow University, West China Second University Hospital of Sichuan University, West China Hospital of Sichuan University, Key Laboratory of Guangdong Province, Third Affiliated Hospital of Harbin Medical University, Affiliated Hospital of Xuzhou Medical College, First People's Hospital of Kunshan, Huainan Normal University, Jilin Medical University, Chinese Academy of Agricultural Sciences, First Affiliated Hospital of Dalian Medical University, First Affiliated Hospital of Bengbu Medical College, Second Affiliated Hospital of Zhejiang University, Shenzhen Third People’s Hospital, Hunan Agricultural University, Southern Medical University, Southern Cross University, University of Hong Kong, Emory University, Massachusetts General Hospital, Rush University Medical Center, Hospital do Servidor Público Estadual, Rush University, Harvard Stem Cell Institute
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4394380932