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Additional file 3: of NmeCas9 is an intrinsically high-fidelity genome-editing platform

Year: 2018

Type: dataset

Abstract: Table S2. Summary of potential off-target sites detected by GUIDE-seq analysis using the Bioconductor package GUIDE-seq. The table includes sites for both NmeCas9 (with N4GN3 PAM sequences) and SpyCas9 (with NGG, NGA, and NAG PAM sequences) for the DTS3, DTS7 and DTS8 sgRNAs, as well as for NmeCas9 with the other sgRNAs used in this study. (XLSX 105 kb)

Source: Figshare

DOI: 10.6084/m9.figshare.7428479

Authors: Amrani, Nadia, Gao, Xin, Liu, Pengpeng, Edraki, Alireza, Mir, Aamir, Ibraheim, Raed, Gupta, Ankit, Sasaki, Kanae, Wu, Tong, Donohoue, Paul, Settle, Alexander, Lied, Alexandra, McGovern, Kyle, Fuller, Chris, Cameron, Peter, Fazzio, Thomas, Zhu, Lihua, Wolfe, Scot, Sontheimer, Erik

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W4394429326

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