Additional file 2 of Causality of genetically determined metabolites on anxiety disorders: a two-sample Mendelian randomization study
Year: 2022
Type: dataset
Abstract: Additional file 2: Table S1. The formula used to calculate R2 and F statistic between exposure and outcome; Table S2. Summary statistics of the anxiety disorders; Table S3–S12. Mendelian Randomization estimation for Amino acid(Table S3); Carbohydrate (Table S4); Co-factor or vitamin(Table S5);Energy(Table S6); Lipid(Table S7); Nucleotide (Table S8); Peptide (Table S9); Xenobiotic(Table S10);X(unknow metabolites) (Table S11);known metabolites (Table S12) on the risk of anxiety disorders; Table S13. The characteristics of SNPs and their genetic associations with known metabolites and the anxiety disorders; Table S15. The reverse MR analysis of 1-linoleoylglycerophosphoethanolamine and anxiety disorders using various methods; Table S16. Association of 1linoleoylglycerophosphoethanolamine and additional anxiety disorders GWAS using various methods; Table S14, S17–S21. Summary statistics for the associations of the five metabolites (passed all the sensitivity analyses)-associated SNPs with these exposures and the anxiety disorders from MRC-IEU Consortium; Table S22. Metabolic Pathway Associated with self-reported anxiety; Table S23. Clinical characteristics of participants involved in the study; Table S24. Characteristics of the KORA population related to antihypertensives and lipid-lowering drugs; Table S25. Characteristics and patterns of anti-hyperglycemic treatment of participants with self-reported type 2 diabetes in the KORA F4 study.
Source: Figshare
Institutions: Central South University, China National Hybrid Rice R&D Central Hunan Hybrid Rice Reserch Center, Third Xiangya Hospital, Shenyang Pharmaceutical University, University of Iowa, Shandong University of Traditional Chinese Medicine, Anhui Agricultural University, Johns Hopkins University, Xinjiang Medical University, Public Health Agency of Canada, Capital Medical University, Chinese Academy of Medical Sciences & Peking Union Medical College, Fudan University, Kunming Medical University, Xuan Wu Hospital of the Capital Medical University, Jiangsu University of Science and Technology, Second Affiliated Hospital of Chongqing Medical University, Nanfang Hospital, Guangzhou Women and Children Medical Center, Baotou Teachers College, Nanjing Municipal Center for Disease Control And Prevention, First Hospital of Jilin University, Shenyang Fifth People Hospital, Second Affiliated Hospital of Harbin Medical University, Sericultural Research Institute, Qilu Hospital of Shandong University, Huazhong University of Science and Technology, Southern Medical University, Xi'an Jiaotong University, Guangzhou Medical University, Air Force Medical University, Shihezi University, Tongji University, Shanghai University of Finance and Economics, Cornell University, China-Japan Friendship Hospital, University of Bristol, Chinese Academy of Fishery Sciences, Fujian Agriculture and Forestry University, Chongqing University, Macau University of Science and Technology, Guizhou University
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4394435258