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Supplementary Figure S6 from Low Exposures to Amphibole or Serpentine Asbestos in Germline Bap1-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

Year: 2024

Type: supplementary-materials

Abstract: IHC staining for WT1 (purple) and SMA (brown in top panels; teal in bottom panels) in representative crocidolite-induced and chrysotile-induced MMs from Bap1+/- mice. WT1 stains MM cells, whereas SMA stains CAFs, the latter typically more abundant in chrysotile-induced than crocidolite-induced MMs, as in the examples shown here.

DOI: 10.1158/2767-9764.25563817.v1

Authors: Yuwaraj Kadariya, Eleonora Sementino, Maggie Ruan, Mitchell Cheung, Parham Hadikhani, Hatice U. Osmanbeyoglu, Andres J. Klein-Szanto, Kathy Cai, Joseph R. Testa

Language: English

Topic: Occupational and environmental lung diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4394567134

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