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Supplementary Figure S4 from Low Exposures to Amphibole or Serpentine Asbestos in Germline Bap1-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

Year: 2024

Type: supplementary-materials

Abstract: Tumor immune microenvironment of chrysotile-induced MM from a Bap1+/- mouse. Serial sections of MM stained with several different immune cell markers: CD3 (T cells), CD45R (B cells), F4/80 (macrophages), and NK1.1 (natural killer cells), clockwise starting from upper left. T, B, and NK cells are depleted in tumor, whereas numerous cells in and around the tumor are stained with the macrophage marker F4/80.

DOI: 10.1158/2767-9764.25563823

Authors: Yuwaraj Kadariya, Eleonora Sementino, Maggie Ruan, Mitchell Cheung, Parham Hadikhani, Hatice U. Osmanbeyoglu, Andres J. Klein-Szanto, Kathy Cai, Joseph R. Testa

Language: English

Topic: Occupational and environmental lung diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4394567218

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