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Impact of CRISPR/HDR editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques

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Year: 2024
Type: article
Source: Cell stem cell
DOI: 10.1016/j.stem.2024.04.005
Authors: Byung-Chul Lee, Ashley Gin, Chuanfeng Wu, Komudi Singh, Max Grice, Ryland Mortlock, Diana Abraham, Xing Fan, Yifan Zhou, Aisha AlJanahi, Uimook Choi, Suk See DeRavin, Taehoon Shin, Sogun Hong, Cynthia E. Dunbar
Language: English

Topic: Hematopoietic Stem Cell Transplantation
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute
Awards: Gene Transfer And Ex Vivo Manipulation Of Hematopoietic Cells, Optimization of genetic modification of HSCs in the NHP model and creation of relevant preclinical models of human disease and therapies
OpenAlex ID: W4394607132
FWCI: 1.946
Cites:
Cited by: 7
Related to: 10
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