Work

Genomic Profiling of the Hallmarks of Cancer

Year: 2024

Type: article

Abstract: We review in this paper the hallmarks of cancer (described by Hanahan and Weinberg) from genomic perspective and we give examples of genomic alterations underlying each of the 10 biological characteristics. We explore examples of current FDA approved therapies that target specific pathways belonging to the different hallmarks of cancer. We also propose an addition to the 10 hallmarks of cancer.

Source: Precision Oncogenomics

DOI: 10.1080/28354311.2023.2264176

Authors: Elie G Dib, Michael Bekkerman, Jad Abbas, Mathura Shanmugasundaram, Dibyendu Banerjee, Gang He, Ondrej Slaby, Mohamed Elsherif, Mengxi Ge

Institutions: Trinity Health Ann Arbor Hospital, Central Drug Research Institute, Masaryk Memorial Cancer Institute, Tanta University Hospital, Shanghai Medical College of Fudan University, Fudan University, Huashan Hospital

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4394614835

FWCI: 0.604

Cites: 29

Cited by: 3

Related to: 10