Therapeutic roles of platelet-rich plasma to restore female reproductive and endocrine dysfunction
Year: 2024
Type: article
Abstract: Millions of women worldwide are infertile due to gynecological disorders, including premature ovarian insufficiency, polycystic ovary syndrome, Asherman syndrome, endometrial atrophy, and fallopian tube obstruction. These conditions frequently lead to infertility and have a substantial impact on the quality of life of the affected couples, primarily because of their psychological implications and high financial costs. Recently, using platelets to stimulate cell proliferation and tissue differentiation has emerged as a promising approach in regenerative medicine. Platelet-rich plasma (PRP) shows considerable potential for promoting endometrial hypertrophy and follicle development, making it a promising therapeutic option for tissue repair or replacement. This review provides an overview of the recent advancements and underlying mechanisms of PRP therapy for various female reproductive diseases and presents new therapeutic options for addressing female infertility.
Source: Frontiers in Endocrinology
Authors: Xiaoning Wang, Jin Li, Jin Li, Weiwei Lu, Fangbo Gao, Songling Zhang, Jiajia Li, Jiajia Li
Institutions: First Hospital of Jilin University, Jilin University
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,295
OpenAlex ID: W4394615952