Work

Gene Expression Analysis of a Topical Serum Comprised of Plant-based Adaptogens Developed to Support Homeostasis and Skin Quality.

Year: 2024

Type: article

Abstract: Objective: A topical serum comprised of plant-based adaptogens was purposefully developed to support the ability of the skin to adapt and achieve balance. The study described herein evaluated changes in the expression of target genes related to skin homeostasis following topical exposure. Methods: <0.05) versus control (saline). A linear Fold Change (FC) value >2 was considered statistically significant. Results: were demonstrated (69%; FC=-3.24) indicating inhibition of oxidative stress-induced senescence. Conclusion: epidermal skin model, a serum comprised of plant-based adaptogens demonstrated changes in the expression of target genes that play important roles in skin's ability to respond to stress and achieve homeostasis.

Source: PubMed Central

Authors: Zoe Diana Draelos, Pearl E Grimes, Jacqueline Watchmaker, Diane B Nelson

Institutions: Dermatology Consulting Services, Vitiligo and Pigmentation Institute of Southern California, L'Oreal (United States)

Language: English

Topic: Skin Protection and Aging

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: L'Oreal USA

OpenAlex ID: W4394764544