Work

Assessing Engraftment Following Fecal Microbiota Transplant

Year: 2024

Type: preprint

Abstract: examines how resistant post-FMT recipient's microbiomes are to reverting back to their baseline microbiome. Individually, these criteria each highlight a critical aspect of microbiome engraftment; investigated together, however, they provide a clearer assessment of microbiome engraftment. We discuss the pros and cons of each of these criteria, providing illustrative examples of their application. We also introduce key terminology and recommendations on how FMT studies can be analyzed for rigorous engraftment extent assessment.

Source: PubMed

DOI: 10.48550/arxiv.2404.07325

Authors: Herman, Chloe, Barker, Bridget M., Bartelli, Thais F., Chandra, Vidhi, Krajmalnik-Brown, Rosa, Jewell, Mary, Li, Le, Liao, Chen, McAllister, Florencia, Nirmalkar, Khemlal, Xavier, Joao B., Caporaso, J. Gregory

Institutions: Northern Arizona University, The University of Texas MD Anderson Cancer Center, Arizona State University, Memorial Sloan Kettering Cancer Center

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute

Awards: G4864707165, Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

OpenAlex ID: W4394780720

Cites: 101

Cited by: 2

Related to: 10