Work

Extranodal Natural Killer/T-Cell Lymphoma Masquerading as Chronic Rhinosinusitis in a Native American Man

Year: 2024

Type: article

Abstract: Extranodal natural killer/T-cell lymphoma (ENKTCL) is a rare Epstein-Barr virus–associated malignancy arising from natural killer cells in nonlymphoid tissues, primarily the upper aerodigestive mucosa. It is rare in the United States but is most frequently seen among the Hispanic population. Clinically, ENKTCL often manifests with nonspecific nasopharyngeal symptoms resembling chronic rhinosinusitis (CRS), making it difficult to diagnose. The absence of standard therapy results in challenging therapeutic decisions and poor outcomes. We report a case of ENKTCL in a 67-year-old Native American, non-Hispanic man with a history of relapsing-remitting CRS.

Source: Annals of Internal Medicine Clinical Cases

DOI: 10.7326/aimcc.2023.1208

Authors: Kendra D. Marr, Biagio J. Collura, Rebecca Wig, Dory Arevalo Salazar, Robert Kim

Institution: University of Arizona

Language: English

Topic: Viral-associated cancers and disorders

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4394859844

FWCI:

Cites: 10

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Related to: 10