Work

eLife assessment: Haplotype function score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits

Year: 2024

Type: peer-review

Abstract: Using sequence-determined functional genomic features instead of original genotypes can partially overcome challenges in genetic association studies, such as rare variant exclusion and population structure.

Source: eLife

DOI: 10.7554/elife.92574.3.sa0

Author: Detlef Weigel

Institution: Max Planck Institute for Biology

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4394954526

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