Undernourished Household Contacts Are at Increased Risk of Tuberculosis (TB) Disease, but not TB Infection—a Multicenter Prospective Cohort Analysis
Year: 2024
Type: article
Study design: Observational Study
Abstract: Undernutrition is the leading risk factor for tuberculosis (TB) globally and in India. This multicenter prospective cohort analysis from India suggests that undernutrition is associated with increased risk of TB disease but not TB infection among household contacts of persons with TB.
Source: Clinical Infectious Diseases
DOI: 10.1093/cid/ciae149
Authors: Pranay Sinha, Komala Ezhumalai, Xinyi Du, Chinnaiyan Ponnuraja, Madolyn Rose Dauphinais, Nikhil Gupte, Sonali Sarkar, Amita Gupta, Sanjay Gaikwad, Balamugesh Thangakunam, Mandar Paradkar, Devasahayam J Christopher, Vidya Mave, Vijay Viswanathan, Jerrold J Ellner, Hardy Kornfeld, C R Horsburgh, Chandrasekaran Padmapriyadarsini, Akshay Gupte
Institutions: Boston University, Boston Medical Center, Jawaharlal Institute of Post Graduate Medical Education and Research, Indian Council of Medical Research, National Institute of Research in Tuberculosis, Johns Hopkins University, B. J. Medical College & Sassoon Hospital, Christian Medical College, Vellore, Rutgers Health, Rutgers New Jersey Medical School, University of Massachusetts Chan Medical School
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: Warren Alpert Foundation, CRDF Global, Johns Hopkins University, Wellcome Trust, Department of Biotechnology, Ministry of Science and Technology, India, Indian Council of Medical Research, National Institutes of Health, Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases, Unitaid
Awards: Phenotype, Progression and Immune Correlates of Post-Tuberculosis Lung Disease, G1964676865, G2213747880, G2708542843, G3841778449, G4618788355, G6892297769, G7363738438, G8011032808, G8693164225, G8811804460, Nutritional Interventions to End Tuberculosis among persons with HIV in India (NUTRIENT-India), G983678233
OpenAlex ID: W4395033651