Society of Interventional Radiology Research Reporting Standards for Genicular Artery Embolization
Year: 2024
Type: article
Abstract: Genicular artery embolization (GAE) is an emerging, minimally invasive therapy to address the global burden of knee osteoarthritis (OA) and the unmet needs for medically refractory disease. Although total knee arthroplasty has been a standard intervention for severe cases, GAE is developing into a promising alternative, particularly for patients ineligible for or unwilling to undergo surgery. GAE targets the inflammatory cascade underlying OA pathophysiology by arresting neoangiogenesis and preventing pathological neoinnervation, offering potential pain relief. Although early studies have established safety and short-term effectiveness, ensuing studies are needed to validate long-term safety, durability, and comparative effectiveness and to optimize patient selection, embolic agent selection, and administration techniques. Standardized reporting guidelines are therefore essential to enhance transparency and reproducibility across clinical trials, facilitating data aggregation and comparison. This Society of Interventional Radiology (SIR)-endorsed reporting standards consensus document provides a framework to harmonize future research efforts and to improve the interpretation of outcomes.
Institutions: University of Chicago, University of Chicago Medical Center, Brigham and Women's Hospital, University of Virginia Medical Center, University of Virginia, NYU Langone Health, Inserm, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Paris Cardiovascular Research Center, Albany Stratton VA Medical Center Albany, University of Minnesota, University of Illinois Hospital & Health Sciences System, Royal Berkshire NHS Foundation Trust, University of California, Los Angeles, Los Angeles Medical Center, Stanford Medicine, Stanford University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,200
Funders: Brigham and Women's Hospital, Small Business Innovation Research, Varian Medical Systems, University of Chicago, University of Minnesota, Boston Scientific Corporation, Cook Medical, Association of University Radiologists, Merit Medical Systems, Institut National de la Santé et de la Recherche Médicale, Astellas Pharma, Assistance publique-Hôpitaux de Paris, Sirtex Medical, National Institutes of Health, University of Illinois at Urbana-Champaign, University of California, Los Angeles
OpenAlex ID: W4395689995