eLife assessment: Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress
Year: 2024
Type: peer-review
Abstract: The agr quorum-sensing system links Staphylococcus aureus metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of H 2 O 2 , a crucial host defense against S. aureus.We now report that protection by agr surprisingly extends beyond post-exponential growth to the exit from stationary phase when the agr system is no longer
Source: eLife
Author: Detlef Weigel
Institution: Max Planck Institute for Biology
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,500
Awards: Targeting Pneumococcal Transmission, Mechanisms of pneumococcal persistence during carriage, G251115611, Humanized lung implant mouse model to study Staphylococcus aureus airway interactions, G3977226188, Mechanisms of MRSA intestinal colonization, Host-pathogen interactions during hospital adaptation of MRSA, G5350012682, Cutaneous Biology and Skin Disease Training Program, Mechanisms of Prophage-Mediated Virulence Driving Community-Acquired MRSA Contagion
OpenAlex ID: W4396509007