Supplemental Figure 3 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
Year: 2024
Type: supplementary-materials
Abstract: Supplemental Figure 3. Circos plot and Dendrogram for Top 25 genes. A Circos plot (Panel A) depicts the relative frequency and pairwise co-occurrence of the top 25 genes mutated in patients with MF. The length of the arc corresponds to the frequency of mutations in the first gene, and the width of the ribbon corresponds to the percentage of patients who also had a mutation in the second gene. Pairwise co-occurrence of mutated genes is denoted only once, beginning with the first gene in the clockwise direction. Panels B shows the relative co-occurrence of mutated gene in a hierarchical clustering dendrogram form; the genes on the same branch are co-mutated more frequently. The shorter vertical lines greater the association.
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4396543538