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Supplemental Figure 5 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations

Year: 2024

Type: supplementary-materials

Abstract: Supplemental Figure 5. RNAseq gene expression of select genes. Expression values for differentially expressed genes in both CD34 cell population and mononuclear cell compartment from MF and ET/PV/PrePMF cohorts. Mean and SEM is plotted of the RPKM values for each data set are plotted. ADGRL4 and DNASE1L3 are downregulated in MF and PLEKGH4B, HSPG2, MAMDC2 an DPYSL3 are upregulated in MF. Fold change and P value for the differentially expressed genes are summarized in the table.

DOI: 10.1158/1078-0432.25728716

Authors: Malathi Kandarpa, Dan Robinson, Yi-Mi Wu, Tingting Qin, Kristen Pettit, Qing Li, Gary Luker, Maureen Sartor, Arul Chinnaiyan, Moshe Talpaz

Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4396543554

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