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Supplementary Figure 2 from Spatial Mapping of Hematopoietic Clones in Human Bone Marrow

Year: 2024

Type: supplementary-materials

Abstract: Supplementary Figure 2. Targeted sequencing of BM fragments to identify somatic mutations. (A) Somatic mutations detected in 24 BM fragments selected for targeted sequencing, plotted at their location in the original sectioned specimen, color-coded by detected mutations and labeled with VAF. (B) Correlation of somatic mutations detected by sequencing and confirmed by ddPCR for JAK2 V617F (R2=0.99). (C) Correlation of somatic mutations detected by sequencing and confirmed by ddPCR for TET2 L1081* (R2=0.35).

DOI: 10.1158/2643-3230.25728745

Authors: Andrew L. Young, Hannah C. Davis, Maggie J. Cox, Tyler M. Parsons, Samantha C. Burkart, Diane E. Bender, Lulu Sun, Stephen T. Oh, Grant A. Challen

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4396543763

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