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Figure S6 from Early Immune Remodeling Steers Clinical Response to First-Line Chemoimmunotherapy in Advanced Gastric Cancer

Year: 2024

Type: other

Abstract: Figure S6. (A) UMAP embedding of single cell transcriptomes obtained from all samples in this trial. Labeled are canonical cell types separated by tumor v.s. normal tissue, and by timepoint. (B) Heatmap and (C) UMAP embeddings showing marker gene expression for broad cell types in (A). (D) Broad cell type composition per sample across tumor and normal tissue. (E) Cell type proportions from scSeq data by timepoint in tumor and normal tissue excluding HER2+ patients. (F) Cell type proportions from scSeq data by timepoint and TCGA classification excluding HER2+ patients.

DOI: 10.1158/2159-8290.25728966.v1

Authors: Minae An, Arnav Mehta, Byung Hoon Min, You Jeong Heo, Samuel J. Wright, Milan Parikh, Lynn Bi, Hyuk Lee, Tae Jun Kim, Song-Yi Lee, Jeonghyeon Moon, Ryan J. Park, Matthew R. Strickland, Woong-Yang Park, Won Ki Kang, Kyoung-Mee Kim, Seung Tae Kim, Samuel J. Klempner, Jeeyun Lee

Language: English

Topic: Gastric Cancer Management and Outcomes

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4396544436

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