Work

Author response: Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function

Year: 2024

Type: peer-review

Abstract: Genetic reduction of Numb or Numb/Nubl is linked to deterioration of the Septin cytoskeleton and suggests cytoskeletal abnormalities are the consequences of and contribute to age-related changes in skeletal muscle.

DOI: 10.7554/elife.89424.4.sa3

Authors: Rita De Gasperi, Laszlo Csernoch, Beatrix Dienes, Monika Gonczi, Jayanta K Chakrabarty, Shahar Goeta, Abdurrahman Aslan, Carlos A Toro, David Karasik, Lewis M Brown, Marco Brotto, Christopher Cardozo

Institutions: Icahn School of Medicine at Mount Sinai, University of Debrecen, Columbia University, Bar-Ilan University, The University of Texas at Arlington

Language: English

Topic: Muscle Physiology and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Funders: U.S. Department of Veterans Affairs, New York State Stem Cell Science, National Institutes of Health, Rehabilitation Research and Development Service, National Research, Development and Innovation Office

Awards: G1089383663, G1679570784, G2131474716, G2872972617, G3047040807, G3343611713, G4569913971, G5137034682, G5174589763, G6715448291, G7015593406, G8747181771, G9000206401, G9000270380, G9000329270

OpenAlex ID: W4396579438

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