Work

Supplementary Figure 13 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Year: 2024

Type: supplementary-materials

Abstract: Addition of an extra RGS/APC domain restores APC and β-catenin binding to selected RGS/APC domain variants, and (partially) restores β-catenin regulation

DOI: 10.1158/0008-5472.25736000

Authors: Ruyi Zhang, Shanshan Li, Kelly Schippers, Yunlong Li, Boaz Eimers, Marla Lavrijsen, Ling Wang, Guofei Cui, Xin Chen, Maikel P. Peppelenbosch, Joyce H.G. Lebbink, Ron Smits

Language: English

Topic: Wnt/β-catenin signaling in development and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4396586062

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